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Overview of SPECTRUM GUIs. The set of graphical user interfaces (GUIs) in SPECTRUM created <t>using</t> <t>MATLAB</t> GUIDE to undertake the search process and visualize results. ( a ) Main SPECTRUM GUI to provide general search parameters, ( b ) GUI to tune intact protein mass, ( c ) GUI to specify special fragmentation ions and mass mode in the search process, ( d ) GUI to provide peptide sequence tag (PST) search parameters, and ( e ) GUI to specify instrument-based chemical modification(s) along with terminal modifications. ( f ) GUI to adjust weights in the scoring scheme, ( g – h ) GUIs to provide users with brief as well as detailed results, ( i ) GUI to describe spectral matching details, ( j ) GUI providing a legend for use in detailed result view, and ( k ) GUI for mass spectrum visualization.
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Overview of SPECTRUM GUIs. The set of graphical user interfaces (GUIs) in SPECTRUM created using MATLAB GUIDE to undertake the search process and visualize results. ( a ) Main SPECTRUM GUI to provide general search parameters, ( b ) GUI to tune intact protein mass, ( c ) GUI to specify special fragmentation ions and mass mode in the search process, ( d ) GUI to provide peptide sequence tag (PST) search parameters, and ( e ) GUI to specify instrument-based chemical modification(s) along with terminal modifications. ( f ) GUI to adjust weights in the scoring scheme, ( g – h ) GUIs to provide users with brief as well as detailed results, ( i ) GUI to describe spectral matching details, ( j ) GUI providing a legend for use in detailed result view, and ( k ) GUI for mass spectrum visualization.

Journal: Scientific Reports

Article Title: SPECTRUM – A MATLAB Toolbox for Proteoform Identification from Top-Down Proteomics Data

doi: 10.1038/s41598-019-47724-1

Figure Lengend Snippet: Overview of SPECTRUM GUIs. The set of graphical user interfaces (GUIs) in SPECTRUM created using MATLAB GUIDE to undertake the search process and visualize results. ( a ) Main SPECTRUM GUI to provide general search parameters, ( b ) GUI to tune intact protein mass, ( c ) GUI to specify special fragmentation ions and mass mode in the search process, ( d ) GUI to provide peptide sequence tag (PST) search parameters, and ( e ) GUI to specify instrument-based chemical modification(s) along with terminal modifications. ( f ) GUI to adjust weights in the scoring scheme, ( g – h ) GUIs to provide users with brief as well as detailed results, ( i ) GUI to describe spectral matching details, ( j ) GUI providing a legend for use in detailed result view, and ( k ) GUI for mass spectrum visualization.

Article Snippet: This can, however, be overcome by parallelizing the toolbox or by using MATLAB GPU computing routines.

Techniques: Sequencing, Modification